I have been to a few different orthodontist specialist because of my gum issues. My gums are VERY sensitive and bleed easily. I have a rare condition of ulcers on my gums ever since I was a kid. I can't have any food that is spicy hot even if it's mild, it burns my gums. I was sent to Case Western Reserve in Cleveland and was a guinea pig for a while. Nothing they had me do worked. My wife found an add for this CBD toothpaste and purchased it. My first week of using it I could tell it was working. It seemed to numb the hurt. I also love the toothbrush it came with. I can even put more pressure while brushing now that I've used the toothpaste for a few weeks. I'm not done with my first tube yet and know I will be buying this again. There is only one small spot that is bothering me yet. I'm hoping in time it will go away. I still can't have spicy food, but I'm am extremely happy with the results so far. The best doctors couldn't help me! This toothpaste is!!